CATALYSIS

G&G chapter 16 p 500-525
problems 1-4 are worthwile

First Edition
G&G read chapter 13 pages 424-445 and the box pages 446-7
problems 1,2,4,5

functional classes of proteins

Transition State

Proteases

COLOR CODING:
protease
binding pocket providing specificity
amino acid sidechain of the substrate
aspartate residue

Chymotrypsin
Elastase
Trypsin

Chymotrypsin in detail

host-guest development of an artificial enzyme

lysozyme a lovely tutorial on this enzyme

Abzyme

HIV Protease

HIV protease contains 2 tutorials: select from the contents 1. Enzyme Mechanisms and then Aspartate protease to see the mechanism
2. Studying Protein Structures and HIV-1 Protease to see the structure

VX gas