COENZYMES & PYRUVATE DEHYDROGENASE

2nd ed G&G Chapter 18 586-601
Chapter 20 646-7

1st ed G&G Chapter 19: 603
Chapter 14: 462-479,495-498
pyruvate pathways
AcCoA pathways
vitamins

This is Figure 15.5b from Lehninger, A.L.; Nelson, D.L.; Cox, M.M. Principles of Biochemistry; Worth: New York, 1993; page 450

.

Transketolase with thiamine coenzyme

Casimir Funk?

Thiamine

beriberi

Lipoate oxidized & reduced

Coenzyme A

FAD

NAD+

NADPH

E2 with lipoate and CoA

E3 with s-s FAD & NAD