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| The
Flynn group's research lies at the interface of biomaterials chemistry
and nanoscience. Examples of recent and current projects in the research
group are shown below.
Current
Research Projects
|
Metal
Nanoparticle-Hydrogel Composites |
|
| Thermoresponsive
Polymer Thin Films |
| Formation, Characterization,
and Temporal Stability of Nanoparticle Thin Films
|
Hydrogels
for Environmental Monitoring and Remediation
- Copper
Uptake using Engineered Hydrogels |
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 |
|
 |
Electrochemically-triggered assembly of metal nanoparticles
|
Designing
Viruses for Studies of Liquid-Crystals and Self-Assembly
(with Seth
Fraden at Brandeis University) - Sythesis of Functionalized
Poly(N-isopropylacrylamide) and Analogues
- Conjugation to
Viruses
- Studies of Liquid
Crystalline Phases
|
Top
Student
Researchers |
| Current
(Summer/Fall '07) |
Research
Project |
| Shloka
Ananthanarayanan, '08 |
Functionalized
nanoparticles for cancer therapy (with Andrew
Webb, Biological
Sciences) |
| Alex
J. Bear, '09 |
Temporal stability of gold nanoparticle thin films |
| Gabrielle
N. Gantos,
'10 |
Electrochemically
trigged assembly of metal nanoparticles |
| Linda
M. Guiney, '09 |
Macromolecular
release from thermoresponsive cationic hydrogels |
| Krystal
S. Lee, '08 |
Thermoresponsive hydrogel films for control of surface biofouling |
| Thea
J. Stewart, '07 |
Investigating
the Pb(II) accumulation capabilities of Chlamydomonas reinhardtii |
| Julia
C. Thomas , '09 |
Macromolecular
release from thermoresponsive anionic hydrogels |
| Katie
E. Wagner, '09 |
Cu
(II) uptake by engineered poly(N-isopropyl-acrylamide)-based
hydrogels |
| Former |
Current Position |
| Alissa D. Agnello, '05 |
Instructor of Nanotechnology, North Seattle CC
[MS '07, chemistry, Univ. of Washington] |
| Jessica R. Bell, '06 |
law student, Columbia
Univ. |
| Mimosa S. Burr, '07 |
graduate student (chemistry), Univ.
of Washington |
| Melissa A. Davis, '05 |
medical
student, Medical Univ.
of South Carolina |
| Danielle D. Draper, '07 |
AmeriCorps, New Orleans, Louisiana |
| Ann C. Gaffey,
'06 |
medical student, Georgetown Univ. |
| Leslie E. Gibson, '04 |
-- |
| Jeenah Jung, '04 |
technical
assistant, M.I.T. |
| Michelle Lee, '06 |
graduate student (chemistry), Tufts
Univ. |
| Minkyeong Lee, '06 |
dental student, Harvard
Univ. |
| Julia Y. Lin, '07 |
graduate
student (chemistry), Northwestern
Univ. |
| Ellane J. Park, '06 |
graduate student (chemistry), Columbia
Univ. |
| Frances Y. Pong, '05 |
Cabot
Corp., Bedford, Mass. |
| Munzarin F. Qayyum, '06 |
graduate student (chemistry), Stanford
Univ. |
| Yechiel Robinson, '07 |
-- |
| Koko Takatori, '07 |
graduate
student (science illustration), UC
Santa Cruz |
| Kate G. Walsham, '07 |
teaching
fellow, Oakland, Calif. |
| Ashley M. Weber, '06 |
graduate student (medical sciences), Boston Univ. |
|
(Underline denotes
honors thesis student.)
|
Top
Previous
Research Projects |
Utilized
surface chemical techniques to modify gold electrodes on
implantable semiconductor devices for drug delivery. |
Developed
stimuli-responsive hydrogel and liposome systems for drug delivery. |
Investigated
self-assembly of metal nanoparticles using coiled-coil peptides
and F-actin. |
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|
 |
|
 |
|
- Research Assistant: (1/98–7/01)
at the University of Illinois
at Urbana-Champaign, Urbana, Ill. with Professor
Andrew A. Gewirth
Synthesized and characterized novel metal (Au, Ag, Pd, Pt) nanoparticles stabilized
with inorganic oxoanions (molybdate, tungstate, chromate) for applications in
catalysis. Particles were synthesized using a variety of chemical reduction methods
and characterized with techniques including: electrochemistry, electron microscopy,
and numerous spectroscopies (IR, UV-vis, X-ray photoelectron, energy dispersive
X-ray, and Raman).
|
- Undergraduate Research
Assistant: (5/95–8/96) at St.
Olaf College, Northfield, Minn. with Professors Mary
M. Walczak and John
P. Walters
Studied derivatives of ferroin using UV-Visible spectroscopy
and several electrochemical techniques. Developed software for
integration of spectrometer with computer using LabVIEW. Developed
experiments for instrumental analysis laboratory.
|
Top
Research
Laboratory Equipment |
- quartz crystal
microbalance with dissipation measurement capabilities (QCM-Z500,
KSV Instruments)
- surface analysis
systems (VCA
Optima XE,
AST Products, Inc.)
- potentiostat/galvanostat (EC
Epsilon, BioAnalytical Systems)
- spin coater
(WS-400B-6NPP-LITE,
Laurell Technologies)
|
Top
Funding
|
Henry Dreyfus Teacher-Scholar Award, The Camille and Henry Dreyfus Foundation, “Development of an electrochemical method for triggering the assembly of metal nanoparticles in aqueous solution” 2007–2012 |
|
DMR-Condensed
Matter Physics, National Science Foundation, “Designing
Viruses for Studies of Liquid-Crystals and Self-Assembly” PI:
Seth Fraden, Brandeis University, 2005–2007; Co-PI: Nolan
Flynn, Wellesley College |
|
Petroleum
Research Fund Type G, American Chemical Society, “Using
Macromolecule Release to Characterize Thermoresponsive Hydrogels
Containing Metal Nanostructure” 2005–2007 |
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Welleley College
|
 |
Science
Center |
 Visitors:
Since
Sept. 2006
|
