Presentation Outline

Conclusions
• MRI can be used to provide quantitative information about the distribution of macromolecules in the normal rabbit eye
• MRI demonstrates that a single episode of acute anterior uveitis produces a long-term alteration in the BAB
• Two parameters emerged as reliable, reproducible, and statistically significant indicators of treatment of uveitic rabbit eyes with 1 % prednisolone acetate as compared with saline: anterior chamber peak MRI intensity; ciliary process peak MRI intensity
Looking into the Eye with MRI
Research Collaborators
Student Faculty Research
History of MRI
Principles of MRI
MR Image of Rabbit Eye
Specific Aims
MR Imaging Studies: Specific Aim 1
Contrast-enhanced MRI of Normal Rabbit Eye
Typical Magnevist MRI Results
MR Imaging Studies: Specific Aim 2
What is Anterior Uveitis
MR Imaging Studies: Specific Aim 3
MR Image Regions Selected for Intensity Measurement
Magnevist Flow into Anterior Chamber of Control Rabbit
Magnevist Flow into Anterior Chamber of Treated Rabbit
Magnevist Flow into Ciliary Process of Control Rabbit
Magnevist Flow into Ciliary Process of Treated Rabbit
Summary of Results
Conclusions
Acknowledgements

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  Susan D. Kunk
 Nancy H. Kolodny
 June 25, 2001
 June 25, 2001