Presentation Outline
Contrast Agents Tested
•

Magnevist (gadolinium diethylenetriamine-pentaacetate dimeglumine; Berlex Industries) mw 742
••
Albumin-coupled GdDTPA (synthesized at Wellesley College) mw~60,000
• MS-325 (Epix Medical) low MW but binds reversibly to plasma albumin in vivo
  (Specific Aim 1, continued on next slide)Spec
Looking into the Eye with MRI
Research Collaborators
Student Faculty Research
History of MRI
Principles of MRI
MR Image of Rabbit Eye
Specific Aims
MR Imaging Studies: Specific Aim 1
Contrast-enhanced MRI of Normal Rabbit Eye
Typical Magnevist MRI Results
MR Imaging Studies: Specific Aim 2
What is Anterior Uveitis
MR Imaging Studies: Specific Aim 3
MR Image Regions Selected for Intensity Measurement
Magnevist Flow into Anterior Chamber of Control Rabbit
Magnevist Flow into Anterior Chamber of Treated Rabbit
Magnevist Flow into Ciliary Process of Control Rabbit
Magnevist Flow into Ciliary Process of Treated Rabbit
Summary of Results
Conclusions
Acknowledgements

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  Susan D. Kunk
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 June 25, 2001
 June 25, 2001