Presentation Outline
Characterization of Albumin-Gd-DTPA

Gadolinium content in AGD was determined by metal analysis at Galbraith Laboratories, Inc. (Knoxville, TN)

To determine the relaxivity (1/T1), inversion-recovery experiments were performed on AGD solutions of varying concentrations (0.0065 mM to 0.09 mM) using a 4.7 T 200 MHz Bruker NMR Spectrometer at Wellesley College
The MW of AGD was determined by SDS-PAGE
  (Specific Aim 1, continued on next slide)Spec
Looking into the Eye with MRI
Research Collaborators
Student Faculty Research
History of MRI
Principles of MRI
MR Image of Rabbit Eye
Specific Aims
MR Imaging Studies: Specific Aim 1
Contrast-enhanced MRI of Normal Rabbit Eye
Typical Magnevist MRI Results
MR Imaging Studies: Specific Aim 2
What is Anterior Uveitis
MR Imaging Studies: Specific Aim 3
MR Image Regions Selected for Intensity Measurement
Magnevist Flow into Anterior Chamber of Control Rabbit
Magnevist Flow into Anterior Chamber of Treated Rabbit
Magnevist Flow into Ciliary Process of Control Rabbit
Magnevist Flow into Ciliary Process of Treated Rabbit
Summary of Results
Conclusions
Acknowledgements

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 Susan D. Kunk
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 June 25, 2001
 June 25, 2001