Presentation Outline
Typical Magnevist MRI Results
• Magnevist (742 mg/ml) injected into marginal ear vein of normal rabbit at t=0
• T1-weighted images collected every 7 minutes
• Image signal intensity (SI) analyzed using Bruker ParaVision software
• Sharp immediate increase in ciliary process SI, followed by decrease over next 120 minutes
• Gradual increase in anterior chamber SI, peaking at 60 minutes
•

Small negative fluctuations in posterior chamber SIrad

(Typical Magnevist MRI Results, contin'd on next slide)
Looking into the Eye with MRI
Research Collaborators
Student Faculty Research
History of MRI
Principles of MRI
MR Image of Rabbit Eye
Specific Aims
MR Imaging Studies: Specific Aim 1
Contrast-enhanced MRI of Normal Rabbit Eye
Typical Magnevist MRI Results
MR Imaging Studies: Specific Aim 2
What is Anterior Uveitis
MR Imaging Studies: Specific Aim 3
MR Image Regions Selected for Intensity Measurement
Magnevist Flow into Anterior Chamber of Control Rabbit
Magnevist Flow into Anterior Chamber of Treated Rabbit
Magnevist Flow into Ciliary Process of Control Rabbit
Magnevist Flow into Ciliary Process of Treated Rabbit
Summary of Results
Conclusions
Acknowledgements

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  Susan D. Kunk
 Nancy H. Kolodny
 June 25, 2001
 June 25, 2001